Description

4-Nitro-3-(Trifluoromethyl)Phenol is a versatile aromatic compound featuring both nitro and trifluoromethyl substituents, which impart unique electronic and steric properties. This chemical serves as a critical advanced intermediate in the synthesis of complex molecules, valued for its role in introducing specific functional groups. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical industries for research and development, as well as process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or nitro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Acts as a precursor for the development of specialized dyes and colorants.
• Liquid Crystal and Electronic Materials: Serves as an intermediate in the creation of fluorinated compounds for advanced material science applications.
• Organic Synthesis & Research: A valuable reagent in academic and industrial laboratories for constructing complex molecular architectures and studying reaction mechanisms.

Basic Information

Product Name	4-Nitro-3-(Trifluoromethyl)Phenol
CAS No.	88-30-2
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	3-(Trifluoromethyl)-4-nitrophenol; 4-Nitro-α,α,α-trifluoro-m-cresol; 2-Hydroxy-6-nitrobenzotrifluoride; 2-Nitro-5-hydroxybenzotrifluoride; Phenol, 4-nitro-3-(trifluoromethyl)-; 4-Nitro-3-trifluoromethylphenol; NSC 404087; 88-30-2
EINECS	201-819-6

Quality Control

Our 4-Nitro-3-(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.