Description

Chlorproethazine CAS NO 84-01-5 is a phenothiazine derivative with significant pharmacological activity. This compound serves as a key intermediate in the synthesis of advanced pharmaceutical agents, particularly in the development of neuroleptic and antihistaminic drugs. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) therapeutics and novel chemical entities.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of phenothiazine-based antipsychotic and antiemetic medications.
• Research & Development: Utilized in academic and industrial R&D for studying structure-activity relationships (SAR) of tricyclic compounds and developing new therapeutic candidates.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex molecules through alkylation, acylation, and other functional group transformations.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	Chlorproethazine
CAS No.	84-01-5
Molecular Formula	C19H23ClN2S
Molecular Weight	346.92 g/mol
Synonyms	2-Chloro-10-(3-diethylaminopropyl)phenothiazine; Chlorproethazine Hydrochloride (salt form); Chlorproethazine Base; NSC 70947; RP 4909; Chlorproethazin; 1-Chloro-3-[10H-phenothiazin-10-yl]-N,N-diethylpropan-1-amine
EINECS	201-632-7

Quality Control

Our Chlorproethazine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-purity standards suitable for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.