Description

Orphenadrine is a centrally acting skeletal muscle relaxant with anticholinergic properties, widely recognized for its efficacy in managing musculoskeletal conditions. This active pharmaceutical ingredient (API) is critical for formulators seeking to develop effective therapeutic agents for pain and spasm relief. It is primarily utilized by pharmaceutical manufacturers in the production of prescription medications targeting muscle spasms and associated discomfort.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription muscle relaxant medications.
• Muscle Spasm Treatment: Formulated into tablets and injectables for the relief of acute, painful musculoskeletal conditions.
• Adjunctive Therapy: Used in combination with rest, physical therapy, and other measures for comprehensive musculoskeletal care.
• Generic Drug Manufacturing: Serves as a key component for producers of generic pharmaceutical products.
• Veterinary Medicine: Potential application in veterinary formulations for animal muscle relaxation.
• Research & Development: Used in pharmacological studies and the development of new therapeutic formulations.

Basic Information

Product Name	Orphenadrine
CAS No.	83-98-7
Molecular Formula	C18H23NO
Molecular Weight	269.38 g/mol
Synonyms	Orphenadrine Hydrochloride (common salt form); N,N-Dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine; Biorphen; Brocasipal; Disipal; Mephenamin; Norflex; Norgesic; Orfen; Orfidal; Orofene; X-Otag
EINECS	201-518-5

Quality Control

Our Orphenadrine is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via validated methods such as HPLC. A Certificate of Analysis (COA) is provided with every shipment, confirming compliance with relevant specifications. We support compliance with major pharmacopoeial standards (e.g., USP, EP) and regulatory frameworks including ICH guidelines, REACH, and FDA requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.