Description

1-(5-Bromopyrimidin-2-yl)piperidine-3-carboxylic acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other small molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its bromopyrimidine moiety for structure-activity relationship (SAR) studies.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and tool compounds for studying biological pathways and target engagement.
• Material Science: Acts as a building block for advanced organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, functionalized structure.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-yl)piperidine-3-carboxylic Acid
CAS No.	799283-93-5
Molecular Formula	C10H11BrN4O2
Molecular Weight	299.13 g/mol
Synonyms	Piperidine-3-carboxylic acid, 1-(5-bromo-2-pyrimidinyl)-; 3-Piperidinecarboxylic acid, 1-(5-bromo-2-pyrimidinyl)-; 1-(5-Bromo-2-pyrimidinyl)piperidine-3-carboxylic acid; 1-(5-Bromopyrimidin-2-yl)piperidine-3-carboxylic acid; 799283-93-5; 5-Bromo-2-(3-carboxypiperidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-yl)piperidine-3-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.