Description

4H-Cyclopenta[D]Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile, 5,6,7,8-Tetrahydro-2-Methyl-8-Oxo- is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology: Utilized as a scaffold or probe in the study of enzyme inhibition and protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and novel heterocycle development.

Basic Information

Product Name	4H-Cyclopenta[D]Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile, 5,6,7,8-Tetrahydro-2-Methyl-8-Oxo-
CAS No.	799250-65-0
Molecular Formula	C₁₁H₁₀N₄O
Molecular Weight	214.22 g/mol
Synonyms	5,6,7,8-Tetrahydro-2-methyl-8-oxo-4H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 799250-65-0; Cyclopentapyrazolopyrimidinecarbonitrile derivative; Tetrahydro-2-methyl-8-oxo-4H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 4H-Cyclopenta[2,3]pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 5,6,7,8-tetrahydro-2-methyl-8-oxo-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support development projects with custom purity grades and specifications tailored to your specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and maintaining an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.