Description

α-Defensin 6 CAS NO 799241-26-2 is a small, cationic antimicrobial peptide belonging to the defensin family, a critical component of the innate immune system. This compound is of significant interest for its potent activity against a broad spectrum of pathogens, including bacteria, fungi, and some enveloped viruses. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for immunology research, novel antimicrobial drug development, and as a potential therapeutic agent.

Application

• Immunological Research: Used as a key reagent to study innate immune responses, neutrophil function, and host-pathogen interactions.
• Antimicrobial Drug Discovery: Serves as a lead compound or model for developing new peptide-based antibiotics and antifungals.
• Biomarker Studies: Investigated as a potential biomarker for inflammatory diseases and certain infections.
• Therapeutic Development: Explored for topical applications in wound healing, dermatology, and mucosal defense.
• Vaccine Adjuvant Research: Studied for its immunomodulatory properties to enhance vaccine efficacy.
• Biochemical Assays: Employed in in vitro assays to measure antimicrobial activity and peptide-lipid interactions.

Basic Information

Product Name	α-Defensin 6
CAS No.	799241-26-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Human α-Defensin 6; HD-6; Defensin, Alpha 6; DEFA6; HNP-6; Cryptdin-6 (murine analog); Neutrophil Peptide 6; Antimicrobial Peptide HD6
EINECS	Contact for details

Quality Control

Our α-Defensin 6 is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including purity assessment by HPLC and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Endotoxin Level	< 1.0 EU/mg
Biological Activity	Assayed by antimicrobial activity test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.