Description

5-(3-Methoxyphenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct pyrazolopyrimidine core structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: May be utilized in the development of assay probes to study specific biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	5-(3-Methoxyphenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	797809-13-3
Molecular Formula	C15H10F3N3O3
Molecular Weight	337.26 g/mol
Synonyms	7-(Trifluoromethyl)-5-(3-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 5-(3-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-(3-methoxyphenyl)-7-(trifluoromethyl)-; 797809-13-3; 5-(3-Methoxyphenyl)-7-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(3-Methoxyphenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.