Description

3-Chloro-5-(3-Methoxy-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new compounds with improved efficacy and safety profiles.
• API Development: Integral to the research and development of new Active Pharmaceutical Ingredients (APIs) for potential use in various therapeutic areas.
• Chemical Synthesis Building Block: Provides a versatile pyrazolo[1,5-a]pyrimidine core for constructing more complex heterocyclic molecules in organic and process chemistry.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	3-Chloro-5-(3-Methoxy-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	797809-12-2
Molecular Formula	C₁₅H₉ClF₃N₃O₃
Molecular Weight	371.70 g/mol
Synonyms	3-Chloro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 797809-12-2; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 3-chloro-5-(3-methoxyphenyl)-7-(trifluoromethyl)-; 3-Chloro-5-(3-methoxy-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-5-(3-Methoxy-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.