Description

3-Chloro-5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a pyrazolopyrimidine core with cyclopropyl and trifluoromethyl substituents, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

This specialized intermediate serves as a versatile scaffold in sophisticated organic synthesis. Key application scenarios include:

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Chemical Biology Probe Synthesis: Employed to create molecular tools for studying biological pathways and target engagement.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for bespoke chemical synthesis services for clients in life sciences.

Basic Information

Product Name	3-Chloro-5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	797809-11-1
Molecular Formula	C11H7ClF3N3O2
Molecular Weight	305.64 g/mol
Synonyms	3-Chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 797809-11-1; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 3-chloro-5-cyclopropyl-7-(trifluoromethyl)-; 3-Chloro-5-cyclopropyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), tailored to meet the specific requirements of research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.