Description

6-Chloro-2,3-Difluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents adjacent to the reactive aldehyde group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where the difluoro motif can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the halogenated benzaldehyde core contributes to potent biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, where fluorine atoms improve charge transport and thermal stability.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, including high-performance resins and engineering plastics.
• Organic Synthesis & Catalysis: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a starting material for heterocyclic chemistry, enabling the creation of diverse chemical libraries.

Basic Information

Product Name	6-Chloro-2,3-Difluorobenzaldehyde
CAS No.	797791-33-4
Molecular Formula	C7H3ClF2O
Molecular Weight	176.55 g/mol
Synonyms	2,3-Difluoro-6-chlorobenzaldehyde; 6-Chloro-2,3-difluorobenzenecarboxaldehyde; Benzaldehyde, 6-chloro-2,3-difluoro-; 2-Chloro-5,6-difluorobenzaldehyde (alternative numbering); 797791-33-4; 6-Chloro-2,3-difluoro-benzaldehyde
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,3-Difluorobenzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, GC for residual solvents, and NMR/IR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.