Description

5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine, 4-Chloro-6,7-Dihydro-2-(3-Pyridinyl)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This heterocyclic compound is valued for its role as a critical building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex, high-value APIs requiring fused heterocyclic systems.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition and receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials and commercial APIs.

Basic Information

Product Name	5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine, 4-Chloro-6,7-Dihydro-2-(3-Pyridinyl)-
CAS No.	796067-64-6
Molecular Formula	C14H10ClN3S
Molecular Weight	287.76 g/mol
Synonyms	4-Chloro-2-(pyridin-3-yl)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine; 4-Chloro-2-(3-pyridinyl)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine; 796067-64-6; 4-Chloro-2-(3-pyridyl)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine; 3-Pyridinyl, 4-chloro-6,7-dihydro-2-(3-pyridinyl)-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine, 4-Chloro-6,7-Dihydro-2-(3-Pyridinyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.