Description

2-(Chloromethyl)-9-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a versatile synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of complex active pharmaceutical ingredients (APIs) requiring the pyrido[1,2-a]pyrimidin-4-one core structure.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-(Chloromethyl)-9-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One (Saltdata: Free)
CAS No.	796067-44-2
Molecular Formula	C10H9ClN2O
Molecular Weight	208.65 g/mol
Synonyms	9-Methyl-2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one; 2-(Chloromethyl)-9-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one, 2-(chloromethyl)-9-methyl-; CAS 796067-44-2; 796067-44-2
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-9-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.