Description

5-Chloro-6-(Chloromethyl)Pyrimidin-4(3H)-One is a versatile and highly functionalized pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its reactive chloromethyl and chloro substituents make it an invaluable intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used as a building block for developing new herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a core intermediate in the multi-step synthesis of complex, high-value APIs.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers and functional materials.

Basic Information

Product Name	5-Chloro-6-(Chloromethyl)Pyrimidin-4(3H)-One
CAS No.	792909-14-9
Molecular Formula	C5H4Cl2N2O
Molecular Weight	179.00 g/mol
Synonyms	4(3H)-Pyrimidinone, 5-chloro-6-(chloromethyl)-; 5-Chloro-6-(chloromethyl)-4(3H)-pyrimidinone; 5-Chloro-6-chloromethylpyrimidin-4-ol; 5-Chloro-6-chloromethyl-4-hydroxypyrimidine; 5-Chloro-6-(chloromethyl)-4-hydroxypyrimidine; 5-Chloro-6-(chloromethyl)pyrimidin-4-ol; 5-Chloro-6-chloromethyl-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-(Chloromethyl)Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.