Description

5-Chloro-6-((2-Iminopyrrolidin-1-Yl)Methyl)-5,6-Dihydropyrimidin-4(3H)-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Potential application in the design and synthesis of inhibitors targeting specific protease enzymes, given its pyrimidinone core structure.
• Kinase Inhibitor Synthesis: Employed in the research and development of potential kinase inhibitors for oncology and other therapeutic areas.
• Custom Synthesis & Scale-Up: Available for custom synthesis projects, from milligram to kilogram scale, supporting process development and scale-up activities.
• Biochemical Research: May be used as a tool compound or reference standard in biochemical assays to study enzyme function and mechanism.

Basic Information

Product Name	5-Chloro-6-((2-Iminopyrrolidin-1-Yl)Methyl)-5,6-Dihydropyrimidin-4(3H)-One Hydrochloride
CAS No.	792909-12-7
Molecular Formula	C9H12ClN4O·HCl
Molecular Weight	265.13 g/mol (Free base: 228.67 g/mol)
Synonyms	5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-5,6-dihydro-4(3H)-pyrimidinone hydrochloride; 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)-5,6-dihydro-4(3H)-pyrimidinone hydrochloride; 5-Chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-3,4,5,6-tetrahydropyrimidin-4-one hydrochloride; 792909-12-7; 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)-3,4,5,6-tetrahydropyrimidin-4-one HCl
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-((2-Iminopyrrolidin-1-Yl)Methyl)-5,6-Dihydropyrimidin-4(3H)-One Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under conditions that minimize exposure to ambient humidity and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.