Description

2-Hydroxy-4-(4-Pyridinyl)-5-Pyrimidinecarboxylic Acid Hydrate is a heterocyclic carboxylic acid derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both pyridine and pyrimidine rings, makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, oncology, and antiviral applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that require specific heterocyclic scaffolds.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: A potential monomer or additive for creating polymers with specific electronic or optical properties.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Hydroxy-4-(4-Pyridinyl)-5-Pyrimidinecarboxylic Acid Hydrate
CAS No.	791585-99-4
Molecular Formula	C10H7N3O3 · xH2O
Molecular Weight	217.18 g/mol (Anhydrous basis)
Synonyms	4-(4-Pyridinyl)-2-hydroxy-5-pyrimidinecarboxylic acid hydrate; 5-Pyrimidinecarboxylic acid, 2-hydroxy-4-(4-pyridinyl)-, hydrate; 2-Hydroxy-4-(4-pyridyl)pyrimidine-5-carboxylic acid hydrate; 4-Pyridin-4-yl-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid hydrate; 791585-99-4 (CAS hydrate); 2-Hydroxy-4-(4-pyridinyl)pyrimidine-5-carboxylic acid monohydrate (common hydrate form).
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-(4-Pyridinyl)-5-Pyrimidinecarboxylic Acid Hydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for water content, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment. We can support development projects with custom purity grades and analytical method development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Anhydrous basis)
Water Content (KF)	≤ 5.0% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.