Description

Renin Substrate 1 Trifluoroacetate Salt is a high-purity synthetic peptide sequence designed for biochemical and pharmacological research. This compound serves as a specific and sensitive substrate for the enzyme renin, a key target in cardiovascular research and hypertension studies. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors requiring reliable, well-characterized reagents for enzyme activity assays, inhibitor screening, and method development.

Application

• Renin Enzyme Activity Assays: Primary substrate for in vitro kinetic studies and enzymatic activity measurements.
• High-Throughput Screening (HTS): Used in pharmaceutical discovery to identify and characterize novel renin inhibitors for cardiovascular drugs.
• Biochemical Research: Fundamental tool for studying the renin-angiotensin system (RAS) pathway and its role in blood pressure regulation.
• Diagnostic Kit Development: A key component in the formulation of clinical diagnostic assays for renin activity in plasma samples.
• Quality Control & Validation: Employed as a reference standard in QC laboratories to validate assay performance and equipment calibration.
• Academic & Institutional Research: Supports basic and applied research in physiology, pharmacology, and molecular biology.

Basic Information

Product Name	Renin Substrate 1 Trifluoroacetate Salt
CAS No.	791068-69-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Renin Substrate I TFA Salt; Prorenin Tetradecapeptide TFA Salt; DRVYIHPFHLLVYS TFA Salt; Angiotensinogen (1-14) TFA Salt; Renin Substrate Tetradecapeptide (porcine) TFA Salt; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser TFA Salt
EINECS	Contact for details

Quality Control

Our Renin Substrate 1 Trifluoroacetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.