Description

1-Palmitoyl-2-Linoleoyl-3-Phosphatidylethanolamine is a high-purity, synthetic phospholipid belonging to the phosphatidylethanolamine (PE) class, a fundamental component of biological membranes. This compound is critical for research and development in advanced lipid-based delivery systems due to its defined structure and consistent quality. It is primarily utilized by scientists and manufacturers in the pharmaceutical, nutraceutical, and biotechnology sectors for applications ranging from liposome formulation to membrane biophysics studies.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural lipid for creating stable, uniform vesicles for drug and nucleic acid (e.g., mRNA) delivery.
• Membrane Biophysics Research: Used as a standard or model lipid to study membrane fluidity, fusion, and protein-lipid interactions in controlled experiments.
• Cell Culture & Reconstitution Studies: Employed to supplement media or create synthetic membranes for studying cellular processes and membrane protein function.
• Pharmaceutical Excipient: Acts as a biocompatible emulsifier or solubilizing agent in advanced parenteral and topical formulations.
• Diagnostic Reagent Development: Serves as a component in diagnostic kits and assays that involve membrane-based detection mechanisms.
• Nutraceutical Encapsulation: Used to develop liposomal delivery systems for vitamins, antioxidants, and other sensitive bioactive compounds to enhance bioavailability.

Basic Information

Product Name	1-Palmitoyl-2-Linoleoyl-3-Phosphatidylethanolamine
CAS No.	14018-09-8
Molecular Formula	C39H74NO8P
Molecular Weight	716.0 g/mol
Synonyms	PE(16:0/18:2); 1-Hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine; (16:0-18:2) PE; PLPE; Phosphatidylethanolamine (16:0/18:2); 1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine; L-α-Phosphatidylethanolamine, 1-palmitoyl-2-linoleoyl-; sn-Glycero-3-phosphoethanolamine-N-(1-palmitoyl-2-linoleoyl)
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Linoleoyl-3-Phosphatidylethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and cGMP-guided applications. A detailed Certificate of Analysis (COA) providing full specifications and test results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, ethanol; insoluble in water
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.