Description

1-Oleoyl-2-Palmitoylphosphatidylcholine (OPPC) is a defined, semi-synthetic phospholipid that serves as a critical building block for advanced lipid-based formulations. This compound is valued for its consistent composition, which provides superior control over the physical and chemical properties of the final product compared to natural lecithin mixtures. It is essential for research and development in the pharmaceutical, nutraceutical, and cosmetic industries, where precise lipid architecture is required for applications such as drug delivery systems and biomembrane studies.

Application

• Liposome & Nanoparticle Formulation: A key component for creating uniform, stable liposomes and lipid nanoparticles (LNPs) used in drug and vaccine delivery.
• Biomembrane Research: Used as a standard or model phospholipid in studies of membrane biophysics, permeability, and protein-lipid interactions.
• Pharmaceutical Excipient: Employed in the development of parenteral and topical formulations to enhance solubility and bioavailability of active pharmaceutical ingredients (APIs).
• Cosmetic Actives Carrier: Functions as a high-performance emulsifier and penetration enhancer in advanced skincare and cosmetic products.
• Nutraceutical Delivery Systems: Incorporated into supplements for the targeted delivery of fat-soluble vitamins and other bioactive compounds.
• Diagnostic Reagents: Used in the preparation of reagents and calibrators for clinical diagnostics and analytical assays.

Basic Information

Product Name	1-Oleoyl-2-Palmitoylphosphatidylcholine
CAS No.	17118-56-8
Molecular Formula	C44H86NO8P
Molecular Weight	788.13 g/mol
Synonyms	OPPC; POPC (common trade name variant); 1-Oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine; (2R)-2-[(9Z)-Octadec-9-enoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate; Phosphatidylcholine (16:0/18:1); PC(16:0/18:1(9Z)); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (structural isomer); Lecithin, 1-oleoyl-2-palmitoyl-
EINECS	Contact for details

Quality Control

Our 1-Oleoyl-2-Palmitoylphosphatidylcholine is produced under strict quality management systems. Each batch is analyzed to ensure high purity and consistency, with specifications suitable for research and cGMP-guided formulation development. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the sealed vial to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
1-Palmitoyl-2-Oleoyl Isomer Content	≥ 95.0% (of total PC)
Lyso-Phosphatidylcholine	≤ 1.0%
Solvent Residues	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 3.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.