Description

2-(Palmitoyloxy)-3-(Stearoyloxy)Propyl 2-(Trimethylammonio)Ethyl Phosphate is a high-purity synthetic phospholipid derivative, also known as a cationic lipid. This compound is valued for its unique amphiphilic structure, which enables it to form stable complexes with nucleic acids and other biomolecules. It is primarily sought after by research institutions and pharmaceutical developers for advanced applications in drug delivery systems, particularly in the formulation of lipid nanoparticles (LNPs) for mRNA vaccines and gene therapies. The product's consistent quality and reliable supply are critical for ensuring reproducible results in sensitive biotechnological processes.

Application

• Lipid Nanoparticle (LNP) Formulation: A key cationic lipid component for encapsulating and delivering mRNA, siRNA, and other nucleic acid therapeutics.
• Gene Delivery & Transfection Reagents: Used in the development of non-viral vectors for in vitro and in vivo gene transfer studies.
• Pharmaceutical Research: Serves as a critical raw material in pre-clinical and clinical-stage research for novel drug delivery platforms.
• Biomimetic Membrane Studies: Employed in model membrane systems to study cell membrane interactions and dynamics.
• Cosmetic & Dermatological Formulations: Acts as a conditioning and stabilizing agent in high-end skincare products for enhanced active ingredient delivery.

Basic Information

Product Name	2-(Palmitoyloxy)-3-(Stearoyloxy)Propyl 2-(Trimethylammonio)Ethyl Phosphate
CAS No.	10589-48-7
Molecular Formula	C44H88NO8P
Molecular Weight	790.14 g/mol
Synonyms	DSPC-Cationic Lipid; 1,2-Distearoyl-3-palmitoyl-rac-glycerophosphocholine analog; Cationic Phosphatidylcholine Derivative; (2-(Palmitoyloxy)-3-(stearoyloxy)propyl) 2-(trimethylammonio)ethyl phosphate; PS-Cationic Lipid; N/A
EINECS	Contact for details

Quality Control

Our 2-(Palmitoyloxy)-3-(Stearoyloxy)Propyl 2-(Trimethylammonio)Ethyl Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and biotechnology research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant guidelines for advanced therapeutic medicinal products (ATMPs).

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. Allow the sealed container to reach room temperature before opening to prevent condensation and hydrolysis. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.