Description

Linoleoyl Coenzyme A is a critical biochemical intermediate, specifically a thioester derivative of linoleic acid and coenzyme A. This compound plays an essential role in the metabolism of polyunsaturated fatty acids, serving as a key substrate for enzymatic reactions in lipid biosynthesis and β-oxidation pathways. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and biochemical synthesis sectors for studying and modulating lipid metabolism.

Application

• Biochemical Research: A vital substrate for studying the enzymatic activity of acyl-CoA desaturases, elongases, and other lipid-modifying enzymes.
• Pharmaceutical Development: Used in high-throughput screening assays to identify potential drug candidates targeting metabolic disorders like obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD).
• Metabolic Pathway Analysis: Essential for in vitro reconstruction and investigation of the fatty acid oxidation and elongation pathways.
• Enzyme Kinetics & Characterization: Serves as a standard or reagent for determining the kinetic parameters (Km, Vmax) of specific acyl-CoA utilizing enzymes.
• Lipidomics & Metabolomics: Used as a reference standard in mass spectrometry-based profiling of acyl-CoA pools within cells and tissues.
• Synthetic Biology: A building block for the enzymatic synthesis of more complex, labeled, or modified lipid compounds in engineered systems.

Basic Information

Product Name	Linoleoyl Coenzyme A
CAS No.	13673-87-5
Molecular Formula	C39H66N7O17P3S
Molecular Weight	1057.94 g/mol
Synonyms	Linoleoyl-CoA; (9Z,12Z)-Octadecadienoyl-CoA; Coenzyme A, S-(9Z,12Z)-1-oxooctadeca-9,12-dien-1-yl ester; Linoleoyl-coenzyme A; 9-cis,12-cis-Linoleoyl-CoA; C18:2-CoA (δ9, δ12); Linoleic acid CoA ester
EINECS	Contact for details

Quality Control

Our Linoleoyl Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We adhere to a rigorous quality management system to support the needs of the global scientific community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO, and ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.