Description

Adrenodoxin is a crucial iron-sulfur protein that functions as an electron transfer intermediate in mitochondrial cytochrome P450 systems. Its primary commercial value lies in its essential role as a research reagent for studying steroid hormone biosynthesis and drug metabolism pathways. This high-purity protein is indispensable for pharmaceutical R&D, academic research in biochemistry, and the development of in vitro diagnostic assays targeting endocrine function.

Application

• Biochemical Research: A key reagent for in vitro studies of mitochondrial cytochrome P450 enzymes, particularly those involved in steroidogenesis (e.g., CYP11A1, CYP11B1).
• Pharmaceutical Development: Used in drug metabolism and toxicity screening assays to understand electron transport mechanisms in hepatic and adrenal systems.
• Enzyme Reaction Reconstitution: Essential for reconstituting active steroidogenic enzyme complexes to study catalytic mechanisms and inhibitor effects.
• Diagnostic Kit Component: Serves as a critical component in specialized diagnostic kits for researching disorders related to adrenal function.
• Protein-Protein Interaction Studies: Utilized to investigate its specific binding and electron transfer interactions with adrenodoxin reductase and cytochrome P450 isoforms.
• Reference Standard: Acts as a purity standard in electrophoretic (SDS-PAGE) and chromatographic (HPLC) analyses for related proteins.

Basic Information

Product Name	Adrenodoxin
CAS No.	12687-22-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Adrenal Ferredoxin; Adrenal Iron-Sulfur Protein; Adrenodoxin, Bovine; ADX; Ferredoxin 1; FDX1; Iron-Sulfur Protein Adrenodoxin; Electron Transfer Flavoprotein
EINECS	Contact for details

Quality Control

Our Adrenodoxin is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high biological activity. Each lot is characterized for purity, identity, and functional integrity, aligning with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing specifications such as purity (by SDS-PAGE and HPLC), protein concentration, and activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / MS)	Conforms to standard
Purity (SDS-PAGE)	≥ 90%
Purity (HPLC)	≥ 95%
Protein Content (Bradford)	≥ 90% of stated
Biological Activity	Contact for details
Endotoxin Level	< 1.0 EU/μg protein
Solubility	Soluble in appropriate buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.