Description

D-Biotin-D-Sulfoxide CAS NO 10406-89-0 is a specific oxidized derivative of the essential vitamin biotin (Vitamin B7). This compound is significant in biochemical research and pharmaceutical development, particularly in studies related to biotin metabolism, enzyme cofactor mechanisms, and analytical method development. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, nutraceutical, and life science industries who require high-purity, well-characterized compounds.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of biotin and its metabolites in drug substances and finished products via HPLC, LC-MS, or other analytical techniques.
• Biochemical Research: Employed as a key reagent in studying biotinidase activity, biotin transport mechanisms, and the role of biotin sulfoxides in metabolic pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a synthetic precursor or a controlled impurity in the manufacturing of biotin-based pharmaceuticals and high-potency supplements.
• Diagnostic Kit Development: Utilized in the formulation of calibration standards and controls for clinical diagnostic assays measuring biotin levels or related enzyme functions.
• Nutraceutical Analysis: Serves as an analytical standard to ensure the purity, potency, and stability of biotin in complex vitamin formulations and dietary supplements.

Basic Information

Product Name	D-Biotin-D-Sulfoxide
CAS No.	10406-89-0
Molecular Formula	C10H16N2O4S
Molecular Weight	260.31 g/mol
Synonyms	(+)-Biotin D-Sulfoxide; D-Biotin Sulfoxide; Biotin Sulfoxide; Vitamin B7 Sulfoxide; Vitamin H Sulfoxide; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid, 3-oxide, (3aS,4S,6aR)-; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-ylvaleric acid 3-oxide
EINECS	Contact for details

Quality Control

Our D-Biotin-D-Sulfoxide is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and manufacturing use. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, it is recommended to store the material under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.