Description

1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Sodium Salt) is a high-purity, synthetic lysophospholipid, specifically a sodium salt of a lysophosphatidic acid (LPA) analogue. This compound serves as a critical biochemical tool and research standard for studying lipid signaling pathways, membrane biophysics, and enzyme kinetics. It is essential for researchers and formulators in pharmaceutical development, lipidomics, and advanced biomaterial synthesis, where precise molecular structure and purity are paramount for reproducible results.

Application

• Biochemical Research: As a standard and substrate for studying phospholipase A2 (PLA2) and other lipid-metabolizing enzymes.
• Lipidomics & Metabolomics: Used as a reference compound in mass spectrometry for the identification and quantification of lysophospholipids in biological samples.
• Cell Signaling Studies: Investigation of Lysophosphatidic Acid (LPA) receptor interactions and downstream signaling cascades in cell culture models.
• Pharmaceutical Development: A key intermediate or active pharmaceutical ingredient (API) in the research of lipid-based therapeutics and drug delivery systems.
• Membrane Biophysics: Utilized in model membrane systems (e.g., liposomes, bilayers) to study the effects of lysolipids on membrane curvature, stability, and fusion.
• Cosmetic & Dermal Research: Exploration of lipid roles in skin barrier function and the development of advanced topical formulations.

Basic Information

Product Name	1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Sodium Salt)
CAS No.	17618-08-5
Molecular Formula	C19H38NaO7P
Molecular Weight	432.46 g/mol
Synonyms	1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate sodium salt; LPA (16:0) sodium salt; 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphate sodium salt; Lysophosphatidic acid (16:0) sodium salt; Sodium 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate; 1-Palmitoyl LPA sodium salt; sn-Glycero-3-phosphoric acid 1-(hexadecanoate) 2-hydroxy monosodium salt; 2-Hydroxy-3-(phosphonooxy)propyl hexadecanoate sodium salt
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.