Description

1H-Pyrazolo[4,3-D]Pyrimidin-7-Amine,n-Cyclobutyl-3-Ethyl-(9Ci) is a high-purity heterocyclic organic compound, identified by CAS number 790666-57-8, that serves as a critical advanced pharmaceutical intermediate. Its value lies in its complex pyrazolopyrimidine scaffold, which is a privileged structure in medicinal chemistry for designing targeted therapeutics. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a precursor for probes used in enzymatic assays and target validation studies.
• Custom Synthesis: Starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrazolo[4,3-D]Pyrimidin-7-Amine,n-Cyclobutyl-3-Ethyl-(9Ci)
CAS No.	790666-57-8
Molecular Formula	C11H15N5
Molecular Weight	217.27 g/mol
Synonyms	N-Cyclobutyl-3-ethyl-1H-pyrazolo[4,3-d]pyrimidin-7-amine; 3-Ethyl-N-cyclobutyl-1H-pyrazolo[4,3-d]pyrimidin-7-amine; 1H-Pyrazolo[4,3-d]pyrimidin-7-amine, N-cyclobutyl-3-ethyl-; 790666-57-8; 3-Ethyl-7-(cyclobutylamino)-1H-pyrazolo[4,3-d]pyrimidine; 7-(Cyclobutylamino)-3-ethyl-1H-pyrazolo[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-D]Pyrimidin-7-Amine,n-Cyclobutyl-3-Ethyl-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.