Description

1H-Inden-1-Amine,6-Fluoro-2,3-Dihydro-,(1R)-(9Ci) is a chiral, fluorinated indane amine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific stereochemistry and fluorine substitution are critical for biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating novel therapeutic agents and high-performance materials.

Application

• As a chiral intermediate in the synthesis of novel pharmaceutical candidates, particularly in central nervous system (CNS) and oncology research.
• For the development of fluorinated bioactive molecules, leveraging the fluorine atom to modulate potency, selectivity, and ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) properties.
• In asymmetric catalysis and method development, serving as a sophisticated ligand precursor or test substrate.
• Within agrochemical research for the creation of new herbicides or pesticides with enhanced efficacy and environmental profiles.
• As a building block for advanced material science, contributing to the synthesis of specialty polymers or liquid crystals.
• For process chemistry optimization and scale-up studies in fine chemical production.

Basic Information

Product Name	1H-Inden-1-Amine,6-Fluoro-2,3-Dihydro-,(1R)-(9Ci)
CAS No.	790208-54-7
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	(1R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine; (R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine; 6-Fluoro-(1R)-indan-1-amine; (1R)-6-Fluoroindan-1-amine; (R)-6-Fluoroindan-1-amine; 790208-54-7; (R)-1-Amino-6-fluoroindane; (1R)-1-Amino-6-fluoro-2,3-dihydro-1H-indene
EINECS	Contact for details

Quality Control

Our production of 1H-Inden-1-Amine,6-Fluoro-2,3-Dihydro-,(1R)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All materials are fully characterized, and Certificates of Analysis (COA) documenting identity, purity (HPLC/GC), chiral purity, and impurity profiles are provided with each shipment. We support cGMP and ISO compliant manufacturing practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.