Description

2,4(1H,3H)-Pyrimidinedione,1-(6-Aminohexyl)-5-Methyl-(9Ci) is a functionalized pyrimidine derivative, a key heterocyclic scaffold in medicinal chemistry and life science research. This compound matters as a versatile building block for the synthesis of novel nucleoside analogs and pharmaceutical intermediates, offering a reactive aminohexyl side chain for further conjugation. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for drug discovery programs and the development of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral or anticancer nucleoside analogs.
• Bioconjugation & Probe Development: The primary amino group on the hexyl chain enables coupling to fluorescent dyes, affinity tags, or solid supports for biochemical assays.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Chemical Biology Tool: Used to develop enzyme inhibitors or modulators that target nucleotide-binding proteins.
• Agrochemical Research: Potential intermediate for developing new plant growth regulators or pesticides based on modified nucleobases.
• Academic Research: Fundamental studies in organic synthesis, heterocyclic chemistry, and nucleic acid chemistry.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione,1-(6-Aminohexyl)-5-Methyl-(9Ci)
CAS No.	790167-37-2
Molecular Formula	C11H19N3O2
Molecular Weight	225.29 g/mol
Synonyms	1-(6-Aminohexyl)-5-methyluracil; 5-Methyl-1-(6-aminohexyl)uracil; 1-(6-Aminohexyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; N1-(6-Aminohexyl)-5-methyluracil; 5-Methyl-N1-(6-aminohexyl)uracil; Uracil, 1-(6-aminohexyl)-5-methyl-; 1-(6-Azidohexyl)-5-methyluracil (precursor form)
EINECS	Contact for details

Quality Control

Our 2,4(1H,3H)-Pyrimidinedione,1-(6-Aminohexyl)-5-Methyl-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.