Description

1H-Indene-1-Carboxaldehyde,5-Fluoro-2,3-Dihydro-,(1S)-(9Ci) is a chiral, fluorinated indene derivative that serves as a sophisticated building block in advanced organic synthesis. Its unique stereochemistry and functional groups make it a valuable intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom and indene scaffold can enhance biological activity and stability.
• Material Science Precursor: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis, crucial for enantioselective manufacturing processes.
• Chemical Biology Probe: Utilized as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Fine Chemical Production: Serves as a high-value intermediate in custom synthesis and contract manufacturing for specialty chemical applications.

Basic Information

Product Name	1H-Indene-1-Carboxaldehyde,5-Fluoro-2,3-Dihydro-,(1S)-(9Ci)
CAS No.	789631-88-5
Molecular Formula	C10H7FO
Molecular Weight	162.16 g/mol
Synonyms	(1S)-5-Fluoro-2,3-dihydro-1H-indene-1-carboxaldehyde; (S)-5-Fluoroindan-1-carbaldehyde; 5-Fluoro-2,3-dihydro-1H-indene-1-carbaldehyde, (1S)-; (S)-5-Fluoro-1-indanecarboxaldehyde; (1S)-5-Fluoroindane-1-carbaldehyde; 789631-88-5; (S)-5-Fluoro-2,3-dihydro-1H-indene-1-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1H-Indene-1-Carboxaldehyde,5-Fluoro-2,3-Dihydro-,(1S)-(9Ci) is produced under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC-MS, to ensure identity, purity, and enantiomeric excess meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.