Description

1H-Indene-1-Carboxaldehyde,5-Fluoro-2,3-Dihydro-(9Ci) is a specialized fluorinated indene derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in its unique molecular architecture, which incorporates both an aldehyde functional group and a fluorine atom on a partially saturated indene scaffold, enabling precise modifications for creating complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, potentially for central nervous system (CNS) agents, anti-inflammatory, or antiviral applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Asymmetric Synthesis: The chiral center and reactive aldehyde group make it a valuable substrate for catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on the introduction and behavior of fluorine in complex organic systems.

Basic Information

Product Name	1H-Indene-1-Carboxaldehyde,5-Fluoro-2,3-Dihydro-(9Ci)
CAS No.	789631-76-1
Molecular Formula	C10H7FO
Molecular Weight	162.16 g/mol
Synonyms	5-Fluoro-2,3-dihydro-1H-indene-1-carboxaldehyde; 5-Fluoroindan-1-carboxaldehyde; 1-Formyl-5-fluoroindane; 5-Fluoro-2,3-dihydro-1H-indene-1-carbaldehyde; (5-Fluoro-2,3-dihydro-1H-inden-1-yl)methanone (tautomeric form); 789631-76-1; 5-Fluoroindane-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Indene-1-Carboxaldehyde,5-Fluoro-2,3-Dihydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided. Allow the container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.