Description

7-Bromoisoquinoline-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the sulfonamide functional group, enabling the creation of complex molecules with tailored properties. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where sulfonamide groups are pharmacologically active.
• Agrochemical Research: Used to create new sulfonamide-based herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and advanced organic frameworks.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling proteins, or creating activity-based probes for enzyme studies.
• Dye & Pigment Synthesis: Intermediate in the production of specialized dyes and pigments containing sulfonamide or isoquinoline structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects requiring this specific brominated sulfonyl chloride.

Basic Information

Product Name	7-Bromoisoquinoline-5-Sulfonyl Chloride
CAS No.	787575-93-3
Molecular Formula	C9H5BrClNO2S
Molecular Weight	306.56 g/mol
Synonyms	5-Chlorosulfonyl-7-bromoisoquinoline; 7-Bromo-5-isoquinolinesulfonyl chloride; Isoquinoline-5-sulfonyl chloride, 7-bromo-; 7-Bromoisoquinoline-5-sulfonic acid chloride; 787575-93-3; 7-Bromo-isoquinoline-5-sulfonylchloride
EINECS	Contact for details

Quality Control

Every batch of 7-Bromoisoquinoline-5-Sulfonyl Chloride is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research and development needs. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and appearance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.