Description

5-Bromo-4-hydrazinyl-6-(trifluoromethyl)pyrimidine is a high-value, multi-functional heterocyclic building block. This compound matters for its unique trifluoromethyl and bromo substituents, which are critical for modulating the physicochemical and biological properties of advanced molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, especially kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Chemical Biology: Serves as a versatile scaffold for creating chemical probes and tool compounds to study biological pathways.
• Material Science Precursor: Potential building block for the synthesis of specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development candidates.

Basic Information

Product Name	5-Bromo-4-hydrazinyl-6-(trifluoromethyl)pyrimidine
CAS No.	785777-95-9
Molecular Formula	C5H3BrF3N4
Molecular Weight	256.99 g/mol
Synonyms	5-Bromo-4-hydrozinyl-6-(trifluoromethyl)pyrimidine; 4-Hydrazinyl-5-bromo-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-5-bromo-4-hydrozinylpyrimidine; 5-Bromo-6-(trifluoromethyl)pyrimidine-4-hydrazine; 785777-95-9; 5-Bromo-4-hydrazino-6-(trifluoromethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-hydrazinyl-6-(trifluoromethyl)pyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support development and cGMP-grade requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.