Description

4,5-Dibromo-6-(Trifluoromethyl)Pyrimidine, 97% is a high-purity, multi-functional halogenated pyrimidine building block essential for advanced organic synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Serves as a precursor for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atoms are excellent handles for palladium-catalyzed reactions (e.g., Suzuki, Stille) to create complex biaryl structures.
• Fluorine Chemistry: The trifluoromethyl group is a valuable motif for modulating lipophilicity and metabolic stability in bioactive compounds.
• Chemical Library Development: Used in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.

Basic Information

Product Name	4,5-Dibromo-6-(Trifluoromethyl)Pyrimidine, 97%
CAS No.	785777-94-8
Molecular Formula	C5HBr2F3N2
Molecular Weight	315.88 g/mol
Synonyms	4,5-Dibromo-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4,5-dibromopyrimidine; 4,5-Dibromo-6-trifluoromethylpyrimidine; Pyrimidine, 4,5-dibromo-6-(trifluoromethyl)-; 785777-94-8
EINECS	Contact for details

Quality Control

Our 4,5-Dibromo-6-(Trifluoromethyl)Pyrimidine, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the specified standard. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.