Description

5-Bromo-2-Chloro-4-(Trifluoromethyl)Pyrimidine is a high-purity, multi-functional halogenated pyrimidine building block essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Bromo-2-Chloro-4-(Trifluoromethyl)Pyrimidine
CAS No.	785777-92-6
Molecular Formula	C5H2BrClF3N2
Molecular Weight	271.43 g/mol
Synonyms	2-Chloro-5-bromo-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-5-bromo-2-chloropyrimidine; 5-Bromo-2-chloro-4-trifluoromethylpyrimidine; 785777-92-6; Pyrimidine, 5-bromo-2-chloro-4-(trifluoromethyl)-; 2-Chloro-5-bromo-4-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements, including those for cGMP (current Good Manufacturing Practice) applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.