Description

5-Bromo-4-(Trifluoromethyl)Pyrimidine is a high-purity, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the strategic combination of bromine and trifluoromethyl groups on the pyrimidine ring, enabling precise molecular modifications and the introduction of desirable physicochemical properties. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists developing specialty chemicals and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for constructing complex organic frameworks, ligands for catalysis, and monomers for specialty polymers.
• Chemical Biology & Proteomics: Employed as a versatile building block for synthesizing molecular probes, tags, and inhibitors used in biochemical assays and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated trifluoromethyl-pyrimidine derivatives.

Basic Information

Product Name	5-Bromo-4-(Trifluoromethyl)Pyrimidine
CAS No.	785777-88-0
Molecular Formula	C5H2BrF3N2
Molecular Weight	226.98 g/mol
Synonyms	4-(Trifluoromethyl)-5-bromopyrimidine; 5-Bromo-4-trifluoromethylpyrimidine; Pyrimidine, 5-bromo-4-(trifluoromethyl)-; 785777-88-0; 5-Bromo-4-(trifluoromethyl)pyrimidine; 5-Bromo-4-(trifluoromethyl)-pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.