Description

(1S)-2,2,2-Trifluoro-1-[4-(Trifluoromethyl)Phenyl]Ethylamine is a high-value, chiral fluorinated amine building block of significant interest in advanced organic synthesis. Its core value proposition lies in its unique trifluoromethylated aromatic structure, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily needed by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, particularly as a key intermediate in the synthesis of potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in CNS, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the synthesis of fluorinated components for advanced liquid crystal displays (LCDs) due to its stable aromatic core and fluorine content.
• Advanced Material Science: Acts as a precursor for specialty polymers and coatings where fluorine incorporation enhances chemical resistance, thermal stability, and surface properties.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel chiral catalysts and ligands for asymmetric synthesis.
• Positron Emission Tomography (PET) Tracer Precursor: Potential use as a building block for fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Product Name	(1S)-2,2,2-Trifluoro-1-[4-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	785766-87-2
Molecular Formula	C9H7F6N
Molecular Weight	243.15 g/mol
Synonyms	(S)-1-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethanamine; (S)-α-(Trifluoromethyl)-4-(trifluoromethyl)benzylamine; (1S)-1-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethylamine; (S)-2,2,2-Trifluoro-1-(4-trifluoromethylphenyl)ethylamine; (S)-1-(4-Trifluoromethylphenyl)-2,2,2-trifluoroethylamine; (S)-TFMPEA; (S)-Trifluoromethylphenyl Trifluoroethylamine
EINECS	Contact for details

Quality Control

Our (1S)-2,2,2-Trifluoro-1-[4-(Trifluoromethyl)Phenyl]Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere such as nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.