Description

6-Bromo-4-Chloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, heterocyclic organic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the construction of novel drug candidates, particularly in kinase inhibitor programs. It is primarily sought after by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the discovery of targeted therapies for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors and other biologically active compounds.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific biological pathways and protein functions.
• Contract Manufacturing (CMO): Supplied in bulk for use in the cGMP production of active pharmaceutical ingredients (APIs) at various development stages.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry and drug discovery projects.
• Library Synthesis: A valuable building block for creating diverse compound libraries for high-throughput screening (HTS).

Basic Information

Product Name	6-Bromo-4-Chloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	784150-42-1
Molecular Formula	C7H5BrClN3
Molecular Weight	246.49 g/mol
Synonyms	4-Chloro-6-bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 6-bromo-4-chloro-7-methyl-; 6-Bromo-4-chloro-7-methylpyrrolo[2,3-d]pyrimidine; 6-Bromo-4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine; 784150-42-1; BCPMP; Pyrrolopyrimidine bromo-chloro intermediate
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our standard grade meets the stringent requirements for advanced pharmaceutical R&D, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.