Description

4-Hydroxy-L-Isoleucine is a non-proteinogenic amino acid derivative of L-isoleucine, characterized by a hydroxyl group at the 4-position. This unique structural modification imparts significant biological activity, making it a valuable intermediate for advanced pharmaceutical and nutraceutical research. It is primarily sought by manufacturers and R&D teams in the pharmaceutical, dietary supplement, and fine chemical synthesis sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Nutraceutical Research: Investigated for its potential metabolic and glucose-regulating properties in dietary supplement formulations.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies and enzymology research.
• Fine Chemical Synthesis: Serves as a chiral precursor for the asymmetric synthesis of complex organic molecules.
• Cosmeceutical Development: Explored for inclusion in advanced skincare products targeting cellular metabolism.

Basic Information

Product Name	4-Hydroxy-L-Isoleucine
CAS No.	781658-23-9
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S,3S,4S)-4-Hydroxyisoleucine; L-4-Hydroxyisoleucine; (2S,3S,4S)-2-Amino-3-methyl-4-hydroxypentanoic acid; 4-Hydroxy-L-isoleucine; 4-Hydroxyisoleucine; HIL; 4-OH-Ile
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-L-Isoleucine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.