Description

11H-Pyrrolo[2,1-C][1,4]Benzodiazepin-11-One,10-Ethyl-1,2,3,5,10,11A-Hexahydro-,(+)-(9Ci) CAS NO 779982-36-4 is a high-purity, chiral benzodiazepine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological scaffold and key synthetic intermediate for the creation of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new benzodiazepine analogs with optimized efficacy and safety profiles.
• Reference Standard: Employed as a high-purity analytical standard in method development and quality control for related drug substances and products.
• Biochemical Probe: Utilized in pharmacological assays to study receptor binding interactions and understand mechanisms of action related to benzodiazepine receptors.
• Process Chemistry Development: Acts as a key intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic Research: Supports fundamental research in organic synthesis, asymmetric catalysis, and the development of new heterocyclic compounds.

Basic Information

Item	Details
Product Name	11H-Pyrrolo[2,1-C][1,4]Benzodiazepin-11-One,10-Ethyl-1,2,3,5,10,11A-Hexahydro-,(+)-(9Ci)
CAS No.	779982-36-4
Molecular Formula	C16H18N2O
Molecular Weight	254.33 g/mol
Synonyms	(+)-10-Ethyl-1,2,3,5,10,11a-hexahydro-11H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one; (11aS)-10-Ethyl-1,2,3,5,10,11a-hexahydro-11H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one; (S)-10-Ethyl-1,2,3,5,10,11a-hexahydro-11H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one; 10-Ethyl-1,2,3,5,10,11a-hexahydro-11H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one; Chiral Benzodiazepine Derivative; PBD Monomer Analog
EINECS	Contact for details

Quality Control

Our 11H-Pyrrolo[2,1-C][1,4]Benzodiazepin-11-One,10-Ethyl-1,2,3,5,10,11A-Hexahydro-,(+)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.