Description

1,3-Dimethyl-5-(Trifluoromethyl)Pyrido-[2,3-D]Pyrimidine-2,4,7(1H,3H,8H)-Trione is a high-value, heterocyclic organic compound featuring a fused pyrido-pyrimidine-dione core substituted with a trifluoromethyl group. This advanced chemical intermediate is critical for research and development in modern synthetic chemistry, particularly for introducing unique steric and electronic properties into target molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, fused-ring structure.
• Chemical Biology Probe Development: Utilized in creating molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including catalysis and novel heterocycle formation.

Basic Information

Product Name	1,3-Dimethyl-5-(Trifluoromethyl)Pyrido-[2,3-D]Pyrimidine-2,4,7(1H,3H,8H)-Trione
CAS No.	779352-01-1
Molecular Formula	C10H8F3N3O3
Molecular Weight	275.19 g/mol
Synonyms	5-(Trifluoromethyl)-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione; 1,3-Dimethyl-5-(trifluoromethyl)-1H,3H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione; 1,3-Dimethyl-5-trifluoromethylpyrido[2,3-d]pyrimidine-2,4,7-trione; CAS 779352-01-1; 5-Trifluoromethyl-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4,7-trione; 1H,3H,8H-Pyrido[2,3-d]pyrimidine-2,4,7-trione, 1,3-dimethyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 1,3-Dimethyl-5-(Trifluoromethyl)Pyrido-[2,3-D]Pyrimidine-2,4,7(1H,3H,8H)-Trione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.