Description

Ethyl 4-Hydroxy-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic pyrrolopyrimidine class. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule therapeutics.
• Kinase Inhibitor Development: Serves as a core scaffold for creating potential inhibitors for various kinase targets involved in oncology and inflammatory diseases.
• Nucleoside Analogue Synthesis: Used in research to develop modified nucleoside analogues with potential antiviral or anticancer activity.
• Chemical Biology Research: Employed as a tool compound or building block in probe development for studying biological pathways.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with novel modes of action.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and scale-up activities.

Basic Information

Product Name	Ethyl 4-Hydroxy-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylate
CAS No.	779326-74-8
Molecular Formula	C9H9N3O3
Molecular Weight	207.19 g/mol
Synonyms	4-Hydroxy-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester; Ethyl 4-hydroxy-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate; 7-Ethoxycarbonyl-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine-7-carboxylic acid, 4-hydroxy-, ethyl ester; 779326-74-8; Pyrrolopyrimidine derivative
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.