Description

4-(4-Bromophenyl)-2-(Methylsulfanyl)Pyrimidine CAS NO 778646-96-1 is a high-purity, heterocyclic organic compound featuring a brominated phenyl ring and a methylthio substituent, serving as a critical advanced pharmaceutical intermediate and versatile building block in synthetic chemistry. Its unique structure makes it indispensable for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for drug discovery and agrochemical applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific activity profiles.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and heterocyclic chemistry due to the reactive bromine and thioether groups.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the exploration of new synthetic pathways.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for transition metal catalysis.

Basic Information

Product Name	4-(4-Bromophenyl)-2-(Methylsulfanyl)Pyrimidine
CAS No.	778646-96-1
Molecular Formula	C11H9BrN2S
Molecular Weight	281.17 g/mol
Synonyms	4-(4-Bromophenyl)-2-(methylthio)pyrimidine; 2-(Methylsulfanyl)-4-(4-bromophenyl)pyrimidine; 4-(p-Bromophenyl)-2-(methylmercapto)pyrimidine; 4-(4-Bromophenyl)-2-methylsulfanylpyrimidine; 2-Methylthio-4-(4-bromophenyl)pyrimidine; 4-(4-Bromophenyl)-2-(methylsulfanyl)-pyrimidine; 778646-96-1
EINECS	Contact for details

Quality Control

Our 4-(4-Bromophenyl)-2-(Methylsulfanyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.