Description

4-Pyrimidineacetic Acid, α-Amino-1,2,3,6-Tetrahydro-2,6-Dioxo-, Ethyl Ester (9Ci) is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 777790-67-7. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is essential for research and development chemists and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators that incorporate pyrimidine-based structures for enhanced efficacy.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules in custom synthesis and contract manufacturing projects.
• Academic & Industrial R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Bioconjugate Chemistry: Potential use in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its functionalizable amino and ester groups.

Basic Information

Product Name	4-Pyrimidineacetic Acid, α-Amino-1,2,3,6-Tetrahydro-2,6-Dioxo-, Ethyl Ester (9Ci)
CAS No.	777790-67-7
Molecular Formula	C9H11N3O4
Molecular Weight	225.20 g/mol
Synonyms	Ethyl 2-amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidineacetate; 2-Amino-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidineacetic acid ethyl ester; 4-Pyrimidineacetic acid, α-amino-1,2,3,6-tetrahydro-2,6-dioxo-, ethyl ester; Ethyl α-amino-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidineacetate; CAS 777790-67-7; 777790-67-7; 4-Pyrimidineacetic acid, 2-amino-1,2,3,6-tetrahydro-2,6-dioxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Pyrimidineacetic Acid, α-Amino-1,2,3,6-Tetrahydro-2,6-Dioxo-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.