Description

5-Pyrimidinecarboxylicacid,1,4,5,6-Tetrahydro-,Hydrazide(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine-hydrazide core.
• Ligand Synthesis: Employed in the preparation of chelating agents and ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics: Acts as a constrained scaffold or a hydrazide linker in the design of peptide analogs and protease inhibitors.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: A versatile building block for constructing complex heterocycles and specialty chemicals.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,4,5,6-Tetrahydro-,Hydrazide(9Ci)
CAS No.	776274-37-4
Molecular Formula	C5H8N4O
Molecular Weight	140.14 g/mol
Synonyms	1,4,5,6-Tetrahydro-5-pyrimidinecarboxylic acid hydrazide; 1,2,3,6-Tetrahydropyrimidine-5-carbohydrazide; 5-Hydrazinylcarbonyl-1,4,5,6-tetrahydropyrimidine; Tetrahydropyrimidine-5-carboxylic acid hydrazide; 1,4,5,6-Tetrahydropyrimidine-5-carbohydrazide; 5-Pyrimidinecarboxylic acid, 1,4,5,6-tetrahydro-, hydrazide
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylicacid,1,4,5,6-Tetrahydro-,Hydrazide(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.