Description

D-Isovaline, 3-Hydroxy-, Methyl Ester, (R)- (9Ci) CAS NO 775541-31-6 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry and functional groups. This compound is a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-quality, stereochemically defined intermediates for complex synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder therapeutics.
• Peptidomimetics Research: Used in the design and synthesis of peptidomimetics and modified peptides to enhance stability, bioavailability, and biological activity.
• Agrochemical Synthesis: Serves as a building block for creating novel, chiral agrochemicals such as herbicides and fungicides with improved efficacy and selectivity.
• Biochemical Research: Employed as a standard or probe in biochemical studies to investigate enzyme mechanisms, receptor binding, and metabolic pathways.
• Asymmetric Catalysis: Utilized as a ligand or precursor for chiral catalysts in asymmetric synthesis to induce high enantioselectivity.
• Fine Chemical Production: An important intermediate in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	D-Isovaline, 3-Hydroxy-, Methyl Ester, (R)- (9Ci)
CAS No.	775541-31-6
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(R)-Methyl 3-hydroxy-2-methylbutanoate; (R)-Methyl 3-hydroxy-2-methylbutyrate; D-3-Hydroxyisovaline methyl ester; (2R)-2-Methyl-3-hydroxybutyric acid methyl ester; Methyl (R)-3-hydroxy-2-methylbutanoate; 2-Methyl-3-hydroxybutyric acid methyl ester, (R)-; Butanoic acid, 3-hydroxy-2-methyl-, methyl ester, (2R)-
EINECS	Contact for details

Quality Control

Every batch of D-Isovaline, 3-Hydroxy-, Methyl Ester, (R)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with exacting industry standards for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.