Description

Benzenemethanol, α-Ethylidene-4-Fluoro- (9Ci) is a specialized fluorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a unique molecular scaffold that incorporates both a reactive alcohol group and a fluorine atom on an aromatic system, enabling precise modifications for target molecule development. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the fluorine atom can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating fluorinated aromatic cores used in advanced electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or chain modifier to impart specific characteristics like chemical resistance or altered refractive index in high-performance engineering plastics.
• Chemical Biology & Probe Development: Utilized in the design of molecular probes and tags for studying biological systems, leveraging the fluorine atom for 19F NMR spectroscopy applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	Benzenemethanol, α-Ethylidene-4-Fluoro- (9Ci)
CAS No.	775531-62-9
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	4-Fluoro-α-ethylidenebenzenemethanol; (4-Fluorophenyl)(1-hydroxyethylidene)methane; 1-(4-Fluorophenyl)ethan-1-ol (tautomer); α-Ethylidene-4-fluorobenzenemethanol; 4-Fluoro-α-methylbenzyl alcohol (related); p-Fluoro-α-ethylidenebenzyl alcohol; Fluorinated benzyl alcohol derivative; Research compound 775531-62-9
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanol, α-Ethylidene-4-Fluoro- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) that detail identity, purity, and impurity profiles, supporting your regulatory and IP documentation. Our quality systems are designed to meet the stringent requirements of cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its chemical nature, keep away from strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.