Description

3-Chloro-2-Fluoro-6-Hydroxybenzaldehyde is a versatile halogenated aromatic aldehyde building block with significant synthetic utility. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small molecule drug candidates, particularly in medicinal chemistry programs targeting new therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive aldehyde and hydroxyl groups.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags, affinity labels, and other molecular probes for biological research.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-Hydroxybenzaldehyde
CAS No.	775334-13-9
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	2-Fluoro-3-chloro-6-hydroxybenzaldehyde; 6-Hydroxy-3-chloro-2-fluorobenzaldehyde; 3-Chloro-2-fluoro-6-hydroxy-benzaldehyde; Benzaldehyde, 3-chloro-2-fluoro-6-hydroxy-; 3-Chloro-2-fluoro-6-hydroxybenzaldehyde (CAS 775334-13-9)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-6-Hydroxybenzaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.