Description

4-(3-Methoxyphenyl)-8-Methyl-2-[(4-Methylphenyl)Amino]-1,4-Dihydro-6H-Pyrimido[1,2-A][1,3,5]Triazin-6-One is a high-purity, advanced pharmaceutical intermediate belonging to a fused heterocyclic chemical class. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and selectivity of new drug molecules.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against various disease targets.
• Process Chemistry Development: Acts as a reference standard or starting material for scaling up and optimizing synthetic routes in process R&D.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Biochemical Probe Development: Potential use in the design of chemical probes to study enzyme function or protein-protein interactions.

Basic Information

Product Name	4-(3-Methoxyphenyl)-8-Methyl-2-[(4-Methylphenyl)Amino]-1,4-Dihydro-6H-Pyrimido[1,2-A][1,3,5]Triazin-6-One
CAS No.	775291-69-5
Molecular Formula	C22H21N5O2
Molecular Weight	387.44 g/mol
Synonyms	8-Methyl-2-[(4-methylphenyl)amino]-4-(3-methoxyphenyl)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one; 2-[(4-Methylphenyl)amino]-4-(3-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one; 4-(3-Methoxyphenyl)-8-methyl-2-(p-tolylamino)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one; CAS 775291-69-5; Pyrimidotriazinone derivative; Fused heterocyclic amine
EINECS	Contact for details

Quality Control

Our 4-(3-Methoxyphenyl)-8-Methyl-2-[(4-Methylphenyl)Amino]-1,4-Dihydro-6H-Pyrimido[1,2-A][1,3,5]Triazin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to ensure maximum stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.