Description

6-((1S)-1-Aminoethyl)-n-(3,4,5-Trimethoxyphenyl)-1,2,4-Triazin-3-Amine is a high-purity, chiral triazine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or building block for synthesizing novel drug candidates, particularly those targeting complex biological pathways. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research laboratories engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) in therapeutic areas such as oncology and neurology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new drug candidates.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for clinical trial material and commercial manufacturing.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme function and cellular signaling pathways.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Custom Synthesis: A foundational compound for custom chemical synthesis services targeting specialized research needs.

Basic Information

Product Name	6-((1S)-1-Aminoethyl)-n-(3,4,5-Trimethoxyphenyl)-1,2,4-Triazin-3-Amine
CAS No.	774460-88-7
Molecular Formula	C14H19N5O3
Molecular Weight	305.34 g/mol
Synonyms	6-[(1S)-1-Aminoethyl]-N-(3,4,5-trimethoxyphenyl)-1,2,4-triazin-3-amine; (S)-6-(1-Aminoethyl)-N-(3,4,5-trimethoxyphenyl)-1,2,4-triazin-3-amine; 1,2,4-Triazin-3-amine, 6-[(1S)-1-aminoethyl]-N-(3,4,5-trimethoxyphenyl)-; CAS 774460-88-7; 6-(1-Aminoethyl)-N-(3,4,5-trimethoxyphenyl)-1,2,4-triazin-3-amine (S-isomer); Chiral Triazine Amine Derivative
EINECS	Contact for details

Quality Control

Our 6-((1S)-1-Aminoethyl)-n-(3,4,5-Trimethoxyphenyl)-1,2,4-Triazin-3-Amine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.