Description

2,4-Dichloro-6,7-Difluoroquinazoline is a high-value, multi-halogenated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring reactive chlorine and fluorine atoms at strategic positions, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted cancer therapies.
• Agrochemical Synthesis: Used to develop new generations of herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as semiconductors and light-emitting compounds.
• Chemical Biology Probes: Employed in the design of fluorescent tags and activity-based probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized quinazoline scaffolds.

Basic Information

Product Name	2,4-Dichloro-6,7-Difluoroquinazoline
CAS No.	774212-69-0
Molecular Formula	C8H2Cl2F2N2
Molecular Weight	235.02 g/mol
Synonyms	6,7-Difluoro-2,4-dichloroquinazoline; 2,4-Dichloro-6,7-difluoro-quinazoline; Quinazoline, 2,4-dichloro-6,7-difluoro-; 2,4-Dichloro-6,7-difluorochinazolin (German); 2,4-ジクロロ-6,7-ジフルオロキナゾリン (Japanese)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6,7-Difluoroquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.