Description

3-Amino-3-(2-Hydroxy-5-Trifluoromethoxy-Phenyl)-Propionic Acid is a specialized non-proteinogenic amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethoxy-substituted aromatic ring and both amino and carboxylic acid functional groups, makes it a valuable intermediate for creating novel compounds with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide analogs to modulate bioavailability, metabolic stability, and receptor binding affinity.
• Material Science: Potential monomer for the synthesis of specialized polymers and functional materials with unique surface properties.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-Amino-3-(2-Hydroxy-5-Trifluoromethoxy-Phenyl)-Propionic Acid
CAS No.	773123-10-7
Molecular Formula	C10H10F3NO4
Molecular Weight	265.19 g/mol
Synonyms	3-Amino-3-(2-hydroxy-5-(trifluoromethoxy)phenyl)propanoic acid; β-Amino-β-(2-hydroxy-5-trifluoromethoxyphenyl)propionic acid; 2-Hydroxy-5-(trifluoromethoxy)-β-alanine; (R/S)-3-Amino-3-[2-hydroxy-5-(trifluoromethoxy)phenyl]propionic acid; 773123-10-7; Amino-hydroxy-trifluoromethoxyphenylpropionic Acid
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(2-Hydroxy-5-Trifluoromethoxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.