Description

4-Amino-2-Chloropyrimidine-5-Carboxylic Acid is a high-purity, multifunctional pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and carboxylic acid functionalities on a chlorinated pyrimidine core, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), or specialty dyes.
• Bioconjugation Chemistry: The carboxylic acid group enables coupling reactions for labeling biomolecules or creating prodrugs.

Basic Information

Product Name	4-Amino-2-Chloropyrimidine-5-Carboxylic Acid
CAS No.	773109-69-6
Molecular Formula	C5H4ClN3O2
Molecular Weight	173.56 g/mol
Synonyms	2-Chloro-4-aminopyrimidine-5-carboxylic acid; 5-Carboxy-2-chloro-4-aminopyrimidine; 4-Amino-2-chloro-5-pyrimidinecarboxylic acid; 2-Chloro-4-amino-5-pyrimidinecarboxylic acid; 4-Amino-2-chloropyrimidine-5-carboxylate; ACPCA; 773109-69-6
EINECS	Contact for details

Quality Control

Our production of 4-Amino-2-Chloropyrimidine-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring full traceability and compliance with customer-specific requirements and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.